The Ultimate Guide to Paeoniflorin (CAS 23180-57-6): Applications, Benefits, and Sourcing Tips

  • December 17, 2025

Paeoniflorin (CAS 23180-57-6) is a highly valued natural compound that has gained significant attention in the global pharmaceutical and cosmetic industries. Derived primarily from the root of Paeonia lactiflora (Chinese Peony), this natural monoterpene glycoside is renowned for its diverse biological activities.

Whether you are a pharmaceutical researcher, a cosmetic formulator, or a chemical procurement manager, understanding the properties and quality standards of Paeoniflorin is essential for your project’s success.

What is Paeoniflorin? (Introduction to CAS 23180-57-6)

Paeoniflorin, with the chemical formula C23H28O11, is the principal bioactive component found in Paeonia lactiflora Pall. It has been used for centuries in traditional medicine and is now a focal point of modern pharmacological studies.

As a white powder, Paeoniflorin is highly soluble in water and methanol. In the commercial market, it is often supplied as a Paeonia Lactiflora Extract, with purities ranging from 10% for bulk dietary supplements to over 85% (HPLC) for high-end pharmaceutical research and cosmetic formulations.

Key Benefits of Paeonia Lactiflora Extract in Modern Medicine

Modern research has validated several pharmacological effects of Paeoniflorin, making it a critical ingredient in various health solutions:

Anti-inflammatory and Immunomodulatory: Paeoniflorin is widely used in treating autoimmune diseases, such as rheumatoid arthritis, by regulating immune responses.

Neuroprotective Effects: Studies suggest that CAS 23180-57-6 may help protect neurons against oxidative stress, showing potential in Alzheimer’s and Parkinson’s disease research.

Cardiovascular Health: It helps improve blood circulation and inhibits platelet aggregation, contributing to overall heart health.

Paeoniflorin for Skin: Why Cosmetic Brands Are Increasing Demand

In the skincare industry, Paeonia Lactiflora Extract is often referred to as a "natural brightener." Cosmetic chemists favor Paeoniflorin for several reasons:

1,Anti-Aging and Antioxidant: It neutralizes free radicals, reducing the appearance of fine lines and wrinkles.

2,Skin Whitening: By inhibiting melanin production, Paeoniflorin helps in fading dark spots and evening out skin tone.

3,Soothing Properties: Its anti-inflammatory nature makes it ideal for sensitive skin formulations designed to reduce redness and irritation.

 

Technical Specifications: CAS 23180-57-6 Profile

For procurement and R&D, having the right technical data is crucial. Below are the standard specifications for high-quality Paeoniflorin:

Appearance

White powder

Conforms

Paeoniflorin(HPLC)

≥85%

89.65%

Odor

Characteristic

Conforms

Taste

Characteristic

Conforms

Mesh size/Sieve

≥95% pass 80 mesh

80 mesh

Bulk density

≤0.8gm/ml

Conforms

Loss on drying

≤5.0%

2.48%

Residue on Ignition

≤2.0%

0.22%

Identifiable active ingredient

Complies with standards

Conforms

Solvent Residues

USP 467

Conforms

Heavy metals

≤10ppm

Conforms

Lead

≤2ppm

Conforms

Arsenic

≤1ppm

Conforms

Meycury

≤0.1ppm

Conforms

Cadmium

≤1ppm

Conforms

Total plate count

1000cfu/g

Conforms

Yeast&Mold

100cfu/g

Conforms

E.Coli

Negative

Conforms

Salmonella

Negative

Conforms

Staphylococcus

Negative

Conforms

 

How to Choose a Reliable Paeoniflorin Manufacturer?

When sourcing Paeoniflorin (CAS 23180-57-6) from China or international markets, quality consistency is the biggest challenge. To ensure you receive a premium product, consider the following:

Purity Verification: Always request a Certificate of Analysis (COA), HPLC chromatograms, and Mass Spectrometry (MS) data.

Production Capacity: Ensure the supplier can scale from gram-level lab samples to bulk industrial quantities.

Storage and Stability: Paeoniflorin is sensitive to light and moisture. A professional manufacturer will provide vacuum-sealed, light-proof packaging and clear storage instructions (2-8°C recommended).

Compliance: Looking for a professional supplier and provide complete HPLC/MSDS for safe logistics.

Paeoniflorin is more than just a traditional extract; it is a versatile building block for the next generation of medicines and premium skincare products. By understanding its chemical profile and sourcing from a reputable manufacturer, you can ensure the efficacy and safety of your final product.

Looking for high-purity Paeoniflorin (CAS 23180-57-6)? We specialize in the production of Paeonia Lactiflora Extract with customizable purity levels to meet your specific needs.Learn more.

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